Both gums and mucilages are plant hydrocolloids that are similarly formed mainly of galactose, methyl pentose, and pentose sugars joined by glycosidic linkages to uronic acid. A quick reference to plant gums and mucilages used as a. Mucilages are generally normal products of metabolism physiological products, formed within the cell intracellular formation. Gums and mucilages are typically heterogeneous polyuronides with similar composition which upon hydrolysis, they yield sugars such as arabinose, galactose, glucose, mannose, xylose and various uronic acids 1 gums as useful hydrocolloids are also contained in some seed embryos or other plant parts in the case of pectin. The plant gums and mucilages used as tablet binders was shown in table 2 and 3. Mucilages of different sources and their derivatives represent a group of polymers widely used in.
In this way, polysaccharides of diverse origins can be considered together, and the structural relationship of the exudate gums and seed mucilages to other groups. This can be prevented by proper handling and the use of preservatives reduced viscosity storage. The chemistry of plant gums and mucilages hirst 1937. Mucilage in plants plays a role in the storage of water and food, seed germination. Research article fabrication, characterization and.
Both mucilages are acidic polysaccharides with associated protein and minerals. Gums are considered to be pathological products formed following injury to the plant or owing to unfavor. They can form three dimensional networks when come in contact with water. They are not soluble in the common organic solvents. The chemistry of plant gums and mucilages and some related. Although their natural polymeric source, gums and mucilages have certain differences. Application of natural gum as a binder in modern drug delivery submit manuscript.
Article views are the countercompliant sum of full text article downloads since november 2008 both pdf and html across all institutions and individuals. Natural gums and mucilages can also be modified to meet the requirements of drug delivery systems and thus can compete with the synthetic excipients available in the market 3. Gums and mucilages are naturally obtained plant polysaccharides, which possess unique properties such as water swellability, non toxicity, low cost, free availability. Recently investigated natural gums and mucilages as pharmaceutical excipients. Classification of gums and mucilages gums and mucilages are present in high quantities in varieties of plants, animals, seaweeds, fungi and other microbial sources, where they perform a number of structural and metabolic functions.
Use the link below to share a fulltext version of this article with your friends and colleagues. Gums and mucilages obtained from plants accessed the release and rate kinetics of drug or drugs in formulation6. Due to these properties, they find applications in food and nonfood industries. The direction of their movement is always opposite to that of the secretion of mucilage. Approaches in biotechnological applications of natural. Gums and mucilages are present in high quantities in certain plants, animals, seaweeds, fungi and other microbial sources, where they perform a number of structural and metabolic functions. The chemistry of plant gums and mucilages and some related polysaccharides. These microorganisms include protists which use it for their locomotion. The analysis of plant gums and mucilages springerlink. Use of natural gums and mucilages as pharmaceutical excipients. Also the natural excipients are preferred on the synthetic and semisynthetic ones because of their lack of toxicity, low cost, soothing action, availability, and nonirritant nature of the.
Recently investigated natural gums and mucilages as. Now a days, mucilage has got an importance as an pharmaceutical excipient as it is having local availability, biocompatibility, lack of toxicity, low cost, biodegradability and better patient tolerance. Application of natural gum as a binder in modern drug delivery. Versatile excipients for pharmaceutical formulations article pdf available in asian journal of pharmaceutical sciences 45 october 2009 with 6,350 reads how we measure.
Introduction nature has provided us a wide verity of materials to improve and sustain the health of all living things either directly or indirectly. Dietary fibre is naturally present in cereals, fruits, vegetables and nuts. Ten years after the publication of food polysaccharides and their applications, a second edition, revised and expanded, has been assembled with the purpose of bringing a modern view of this fascinating and important subject to chemists, food scientists, and interested students. Natural gums and mucilages are naturally occurring components in plants, which are essentially.
Natural gums and mucilages are hydrophilic colloids, which form dispersion with water and increase the viscosity of continuous phase, so that the solid particles remain suspended in it for a sufficient long time to measure a uniform dose. Introduction the plant is the primary producer but other than this it is useful to humans in many other ways by giving its secretions, juices and other biochemical compounds. Extraction and characterization of okra mucilage as. List of natural gums used as a tablet binder common name botanical name family gum acacia acacia catechu leguminosae9 gum albizia albiziazygia leguminoseae10 gum almond prunuscommunis rosaceae11. An overview by pritam dinesh choudhary and harshal ashok pawar no static citation data no static citation data cite. The aim of this article is to highlight the natural gums and mucilages as natural binding agent in various pharmaceutical dosage form. View and download powerpoint presentations on gums and mucilages ppt. Drug delivery systems, gum, modified release dosage forms, mucilage, pharmaceutical excipients. Gums and mucilages are present in high quantities in verities of plants, animals, seaweeds, fungi and other microbial sources, where they perform a number of. Pathological products formed by plants as results of injury or unfavorable conditions like drought are gums. Moreover, the tremendous orientation of pharma world towards these naturally derived polymers has become a. Besides gums, the constituents of polysaccharides also include mucilages.
Physicochemical, phytochemical and toxicity studies on gum. Studies on the mucilages extracted from okra fruits. The mucilages were extracted from both foods and purified. Gums and mucilages are also frequently used as protective colloids or thickeners. Review article recently investigated natural gums and. The physicochemical properties, methods of analysis and therapeutic functions of dietary fibre are discussed in this paper. Preliminary studies have been conducted to characterise the mucilages chemically, as well as study their viscous behaviour in relation to their use in west african dishes. These natural well as endodermis, some secretary cells as in squill and polymers are applicable in different pharmaceutical also present in the schizogenous sacs 8.
Further mucilage is products of metabolism, no trigger required for. Gums and mucilages are widely used natural materials for conventional and novel dosage forms. Their diverse structural compositions with a broad. Most gums and mucilages yield several monosaccharides on hydrolysis e. Gums, resins and other vegetable saps and extracts heading 2 applies, inter alia, to licorice extract and extract of pyrethrum, extract of hops, extract of aloes and opium. Also, some gums are exuded on the surface of plants, such as gum arabic, gum karaya, and gum tragacanth.
Quantitative evaluation of some physical and chemical. Mucilage is a thick, gluey substance produced by nearly all plants and some microorganisms. Find powerpoint presentations and slides using the power of, find free presentations research about gums and mucilages ppt. Guar gum, which is technically mucilage and not a gum, is found in most legumes beans and is the most widely studied plant mucilage. They are also used in cosmetics, textiles, paints and papermaking 1. Excipients for modified drug delivery system bharat w. The composition of the gums and mucilages is however much more complicated than is. Extraction of mucilage and its comparative evaluation as a. The plant mucilages and gums are secreted by the plant and it is of high industrial importance. Gums can be hydrolysed bygums can be hydrolysed by prolonged boiling withprolonged boiling with dilute acids to yeild adilute acids to yeild a mixture of sugars andmixture of sugars and uronic acids. Polysaccharide rich gums and mucilages are produced by different natural sources such as plants, animals and microbial organisms to fulfil structural and physiological functions.
It is a polar glycoprotein and an exopolysaccharide. Here, we are going to see about these biologically useful. The different available gums and mucilages can be classified as follows. Application of natural gum as a binder in modern drug delivery 38. They are similar to gums except that mucilages are generally normal products of metabolism, formed within the cell intracellular formation andor are produced without injury to the plant. It includes cellulose, hemicellulose, pectic substances, gums, mucilages and lignin etc. Both gums and mucilages are plant hydrocolloids yielding mixture of sugars and uronic acids on hydrolysis. Physicochemical, phytochemical and toxicity studies on gum and mucilage from plant abelmoschus esculentus shankul kumar abstract okra is a popular health food due to its high fiber, vitamin c, and folate content. With the increasing interest in polymers of natural origin, the pharmaceutical world has compliance to use most of them in their formulations. Pharmaceutical applications of various natural gums. Some are completely soluble in water, forming viscous solutions of gels, others swell and absorb considerable quantities of solvent without dissolving.
Review on natural gums and mucilage and their application. Gums readily dissolve in water, whereas, mucilage form slimy masses. Some recently investigated natural gums and mucilages abelmoschus gum. In addition, the plant has been used medicinally in the. Application of natural gum as a binder in modern drug. Review article recently investigated natural gums and mucilages as pharmaceutical excipients. These natural gums and mucilages are preferred over the synthetic ones because they are biocompatible, cheap, and easily available than the synthetic ones. They have been wildly used as tablet binders, emulgents and thickeners in cosmetics and suspensions as filmforming agents and transitional colloids. Natural rubber, balata, guttapercha, guayule, chicle or similar natural gums heading 4001.